This function imputes the start concentration using the log slope method.

Usage

PKNCA_impute_method_start_logslope(
  conc,
  time,
  start,
  end,
  ...,
  options = list()
)

Arguments

conc: Numeric vector of concentrations.
time: Numeric vector of times corresponding to the concentrations.
start: Numeric value indicating the start/dose time.
end: Numeric value indicating the end time.
...: Additional arguments (currently not used).
options: List of options (currently not used).

Value

A data frame with imputed start concentration.

Details

This function adheres to the structure required by the PKNCA package to work with its functionalities. For more information, see the PKNCA Data Imputation Vignette.

Examples

conc <- c(5, 4, 3, 2, 1)
time <- c(1, 2, 3, 4, 5)
start <- 0
end <- 4
PKNCA_impute_method_start_logslope(conc, time, start, end)
#>   conc time
#> 6 6.25    0
#> 1 5.00    1
#> 2 4.00    2
#> 3 3.00    3
#> 4 2.00    4
#> 5 1.00    5