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Export CDISC Data

Source: R/export_cdisc.R
export_cdisc.Rd

This function processes the results from a PKNCA and exports them into CDISC compliant datasets. Attention: All parameters that do no match pptest dataframe will be lost in this pipeline!

Usage

export_cdisc(res_nca, grouping_vars = character(0), flag_rules = NULL)

Arguments

res_nca

Object with results of the NCA analysis.

grouping_vars

Character vector of non-standard grouping variable names to include as additional columns in ADNCA, ADPP, and PP outputs. Defaults to character(0).

flag_rules

Character vector of flag rule exclusion messages applied during NCA (e.g., c("R2ADJ < 0.8", "AUCPEO > 20")). Each entry generates a CRITy/CRITyFL column pair in ADPP, plus PPSUMFL and PPSUMRSN columns. Defaults to NULL (no flags).

Value

A list with two data frames:

pp

A data frame containing the PP (Pharmacokinetic Parameters) domain data.

adpp

A data frame containing the ADPP (Analysis Dataset for Pharmacokinetic Parameters) domain data.

Details

Outputs are the following:

  • pknca_result Output from function call pk.nca() (formatted)

  • pknca_result_raw Output from function call pk.nca() (needs to be merged with upper later on but now we avoid merge conflict)