Check if ocular concomitant medication has laterality missing or laterality field is populated but route is not eye-related.

This check assesses CMCAT = "CONCOMITANT MEDICATIONS" and flags potential ocular records with missing/inconsistent route and laterality: for eye-related CMROUTE ('INTRAVITREAL', 'OPHTHALMIC', etc.), CMLAT is not populated -or- CMROUTE is not eye-related (i.e., not INTRAVITREAL, OPHTHALMIC, TOPICAL, etc.) but CMLAT is LEFT/RIGHT/BILATERAL.

check_cm_cmlat(CM, preproc = identity, ...)

Arguments

CM

Concomitant Medications Dataset for Ophtho Study with variables USUBJID, CMCAT, CMLAT, CMDECOD, CMTRT, CMROUTE, CMSPID (if Present), CMSTDTC (if Present)

preproc

An optional company specific preprocessing script

...

Other arguments passed to methods

See also

Other OPHTH: check_ae_aelat(), check_cm_cmlat_prior_ocular(), check_oe_bcva_1m_late_early_tot(), check_oe_bcva_4m_late_early_tot(), check_oe_bcva_4m_vs_1m_req(), check_oe_bcva_tot_mismatch(), check_oe_sc_lat_count_fingers(), check_pr_prlat(), check_sc_dm_eligcrit(), check_sc_dm_seyeselc()

Author

Monarch Shah (HackR 2021 Team Eye)

Examples

CM <- data.frame(
   USUBJID = 1:7,
   CMCAT = "CONCOMITANT MEDICATIONS",
   CMSTDTC = 1:7,
   CMLAT   = c("Left", "","Bilateral", "", "", "LEFT", ""),
   CMTRT  = c("A", "B", "A", "B", "A", "A", "B"),
   CMDECOD = c("A", "B", "A", "B", "A", "A", "B"),
   CMROUTE = c("","OPHTHALMIC","INTRAVITREAL","INTRAVITREAL", 
               "opHTHALMIC", "INTRaOCULAr", "INTRaOCULAr"),
   CMSPID  = "FORMNAME-R:13/L:13XXXX",
   stringsAsFactors = FALSE)
check_cm_cmlat(CM,preproc=roche_derive_rave_row)
#> [1] FALSE
#> attr(,"msg")
#> [1] "5 record(s) with CMLAT Missing when CM is Eye related, or CMLAT is LEFT/RIGHT/BILATERAL and CMROUTE is not Eye related."
#> attr(,"data")
#>   USUBJID CMSTDTC          RAVE CMLAT CMTRT CMDECOD      CMROUTE
#> 1       1       1 FORMNAME-R:13  Left     A       A             
#> 2       2       2 FORMNAME-R:13           B       B   OPHTHALMIC
#> 3       4       4 FORMNAME-R:13           B       B INTRAVITREAL
#> 4       5       5 FORMNAME-R:13           A       A   opHTHALMIC
#> 5       7       7 FORMNAME-R:13           B       B  INTRaOCULAr

CM <- data.frame(
   USUBJID = 1:5,
   CMCAT = rep("CONCOMITANT MEDICATIONS",5),
   CMSTDTC = 1:5,
   CMLAT   = c("Left", "LEFT","Bilateral", 
               "RIGHT", "RIgHT"),
   CMTRT  = c("A", "B", "A", "B", "A"),
   CMDECOD = c("A", "B", "A", "B", "A"),
   CMROUTE = c("","OPHTHALMIC","INTRAVITREAL",
               "INTRaOCULAr", "opHTHALMIC"),
   stringsAsFactors = FALSE)
check_cm_cmlat(CM)
#> [1] FALSE
#> attr(,"msg")
#> [1] "1 record(s) with CMLAT Missing when CM is Eye related, or CMLAT is LEFT/RIGHT/BILATERAL and CMROUTE is not Eye related."
#> attr(,"data")
#>   USUBJID CMSTDTC CMLAT CMTRT CMDECOD CMROUTE
#> 1       1       1  Left     A       A        

CM <- data.frame(
   USUBJID = 1:5,
   CMCAT = "CONCOMITANT MEDICATIONS",
   CMSTDTC = 1:5,
   CMLAT   = c("Left", "LEFT","Bilateral", "RIGHT", "RIgHT"),
   CMTRT  = c("A", "B", "A", "B", "A"),
   CMDECOD = c("A", "B", "A", "B", "A"),
   #CMROUTE = c("","OPHTHALMIC","INTRAVITREAL","INTRaOCULAr", "opHTHALMIC"),
   stringsAsFactors = FALSE)
check_cm_cmlat(CM)
#> [1] FALSE
#> attr(,"msg")
#> [1] "CM is missing the variable: CMROUTE"